Dr Fiona Murphy
Lecturer
Strathclyde Institute of Pharmacy and Biomedical Sciences
Personal statement
Personal statement
My research focuses on identifying the hazards to human health posed by inhalation exposure to aerosolised particles and nanomaterials. Recent focus is on the development of physiologically-relevant in vitro models to reduce the reliance on rodent models for hazard assessment of novel materials and to improve our understanding of the underlying mechanism of particle-related lung disease.
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Publications
- Evaluation of a bioprinted 3D airway tissue model for toxicity testing of nanomaterials; pathway to integration into a tiered testing strategy for hazard assessment to support safety-by-design
- Lee Yunji, McAllister Katie, Lee Hwa-Rim, Jung Sungjune, Murphy Fiona
- Nano Today Vol 61 (2025)
- https://doi.org/10.1016/j.nantod.2025.102655
- Humanising nanotoxicology : replacement of animal-derived products in the application of integrated approaches to testing and assessment of nanomaterial inhalation hazard
- Fraser Roma, Campbell Keira, Pokorski Pawel, Mackinnon Eve, McAllister Katie, Neves Karla B, Murphy Fiona
- Frontiers in Bioengineering and Biotechnology Vol 13 (2025)
- https://doi.org/10.3389/fbioe.2025.1526808
- Asbestos and disease genomics : is mesothelioma a genomic paradigm?
- Jaurand Marie-Claude, Murphy Fiona, Felley-Bosco Emanuela
- Frontiers in Toxicology Vol 6 (2025)
- https://doi.org/10.3389/ftox.2024.1536344
- Safe-by-design assessment of an SiO2@ZnO multi-component nanomaterial used in construction
- Brunelli A, Serrano-Lotina A, Bañares M A, Alcolea-Rodriguez V, Blosi M, Costa A, Ortelli S, Peijnenburg W, Fito C, Fernandez E G, Hermosilla J S, Soeteman-Hernández L G, Garmendia Aguirre I, Rauscher H, Murphy F, Stone V, Balbuena J, Cormano J M L, Pizzol L, Hristozov D, Marcomini A, Badetti E
- Environmental Science: Nano Vol 12, pp. 762-776 (2025)
- https://doi.org/10.1039/d4en00352g
- Non-cyclic nucleotide EPAC1 activators suppress lipopolysaccharide-regulated gene expression, signalling and intracellular communication in differentiated macrophage-like THP-1 cells
- Wiejak Jolanta, Murphy Fiona A, Barker Graeme, Maffia Pasquale, Yarwood Stephen J
- Cellular Signalling Vol 124 (2024)
- https://doi.org/10.1016/j.cellsig.2024.111444
- Differential roles for the oxygen sensing enzymes PHD1 and PHD3 in the regulation of neutrophil metabolism and function
- Watts Emily, Willison Joseph, Arienti Simone, Sadiku Pranvera, Coelho Patricia, Sanchez-Garcia Manuel, Zhang Ailiang, Murphy Fiona, Dickinson Rebecca, Mirchandani Ananda, Morrison Tyler, Lewis Amy, Vermaelen Wesley, Ghesquiere Bart, Carmeliet Peter, Mazzone Massimilliano, Maxwell Patrick, Pugh Christopher, Dockrell David, Whyte Moira, Walmsley Sarah
- Wellcome Open Research Vol 8 (2024)
- https://doi.org/10.12688/wellcomeopenres.19915.2
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Professional Activities
- SIPBS Open Doors Day
- Chair
- 8/6/2024
- NC3Rs NAMs-Net Launch
- Participant
- 30/4/2024
- MSci external examiner
- Examiner
- 22/3/2024
- Society of Toxicology
- Speaker
- 2024
- Animal Free Research UK Scientific Conference
- Speaker
- 4/10/2023
- NC3Rs Galleria mellonella worksop
- Speaker
- 13/9/2023
Projects
- DTP 2224 University of Strathclyde | McAllister, Katie
- Murphy, Fiona (Principal Investigator) Perrie, Yvonne (Co-investigator) McAllister, Katie (Research Co-investigator)
- 01-Jan-2024 - 01-Jan-2028
- Validation of Scinora serum-free media formulations and Xplace supplement for the development of animal-free NAMs for nanotoxicology
- Murphy, Fiona (Principal Investigator)
- 01-Jan-2024 - 31-Jan-2025
- Generation of physiologically-reelevant mesothelioma tumour spheroids using tunable hydrogel scaffolds for improved preclinical drug screening
- Murphy, Fiona (Principal Investigator)
- 01-Jan-2024 - 31-Jan-2025
- Developing the Chick Chorioallantoic Membrane (CAM) model for hazard assessment of High Aspect Ratio Nanomaterials
- Murphy, Fiona (Principal Investigator)
- 07-Jan-2024 - 06-Jan-2025
- Development of a physiologically-relevant in vitro model of the lung alveolar space, incorporating novel peptide hydrogels as biomimetic extracellular matrix scaffolds
- Murphy, Fiona (Principal Investigator)
- 01-Jan-2023 - 30-Jan-2024
- Development of a physiologically-relevant in vitro model of the lung alveolar space, incorporating novel peptide hydrogels as biomimetic extracellular matrix scaffolds
- Murphy, Fiona (Principal Investigator)
- 01-Jan-2022 - 31-Jan-2024
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Contact
Dr
Fiona
Murphy
Lecturer
Strathclyde Institute of Pharmacy and Biomedical Sciences
Email: f.murphy@strath.ac.uk
Tel: Unlisted